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KMID : 1038820180210020147
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Pediatric Gastroenterology, Hepatology & Nutrition
2018 Volume.21 No. 2 p.147 ~ p.153
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Acute Gastritis and Splenic Infarction Caused by Epstein-Barr Virus
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Jeong Ji-Eun
Kim Kyung-Moon
Jung Hye-Lim
Shim Jae-Won
Kim Deok-Soo
Shim Jung-Yeon
Park Moon-Soo
Park Soo-Kyung
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Abstract
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Epstein-Barr virus (EBV) infection can be presented with various clinical manifestations and different levels of severity when infected. Infectious mononucleosis, which is most commonly caused by EBV infection in children and adoles-cents, is a clinical syndrome characterized by fatigue, malaise, fever, sore throat, and generalized lymphadenopathy. But rarely, patients with infectious mononucleosis may present with gastrointestinal symptoms and complicated by gastritis, splenic infarction, and splenic rupture. We encountered a 16-year-old girl who presented with fever, fatigue, and epigastric pain. Splenic infarction and EBV-associated gastritis were diagnosed by using esophagogas-troduodenoscopy and abdominal computed tomography. Endoscopy revealed a generalized hyperemic nodular lesion in the stomach, and the biopsy findings were chronic gastritis with erosion and positive in situ hybridization for EBV. As splenic infarction and acute gastritis are rare in infectious mononucleosis and are prone to be overlooked, we must consider these complications when an infectious mononucleosis patient presents with gastrointestinal symptom.
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KEYWORD
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Herpesvirus 4, human, Gastritis, Splenic infarction, Infectious mononucleosis
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